Luxury private hotel group Hyatt Corporation is believed to be in discussions to take over the Great Eastern Hotel in London.
The 267-bedroom hotel by Liverpool Street station has a price tag of £150m.
The property is jointly owned by Conran Holdings and property investment company Blackstone Real Estate.
Conran, which runs the hotel's four restaurants, said it would want to continue its involvement in the outlets.
A spokesman for Hyatt Corporation declined to comment.
By Emily Manson
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