Premier Inn has announced it has acquired a site for a 267-bedroom budget hotel at Stratford, located adjacent to the Olympic Stadium.
The Whitbread-owned brand will be making an investment worth £25m and creating approximately 90 jobs.
The hotel will be the closest hotel to the new Stratford International station, which opened in December 2009.
Since the start of 2009, Premier Inn has acquired 13 new London locations at sites ranging from Greenwich to Islington. The new hotels are predominately leasehold with a total value of £160m.
The site in Stratford plus the other new locations will all be open and trading by Summer 2012, boosting Premier Inn's total number of bedrooms by 2,324. In total Premier Inn will have 59 hotels and 8,374 rooms in London by 2012.
Whitbread is expecting to create almost 1,000 new Premier Inn jobs in London between now and Summer 2012.
Alan Parker, chief executive of Whitbread, said: "Securing this first-class location adjacent to the Olympic Stadium is a great result for us. With our expansion over the next two years Premier Inn will have an unrivalled presence across London with more bedrooms in more locations than any other hotel operator."
John Burton, director of Westfield Stratford City, where the hotel will be based, said: "Westfield Stratford City will be projected onto a world stage during the Olympic Games in 2012 and we are creating a new metropolitan hub which will transform east London for the wider community, prompting increased investment and business activity in the area for years to come."
By Janet Harmer
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