Anthony's restaurant in Leeds, run by chef Anthony Flinn, has gone into administration.
The business is one of four in the group to have called in administrators, and up to 70 jobs could be at risk, according to the Huddersfield Daily Examiner.
Flinn originally set up the restaurant in 2004.
After opening that site, Flinn and his father, also called Anthony, extended to three more sites including Piazza by Anthony in the Corn Exchange, Rib Shakk and Anthony's Patisserie in the Victoria Quarter.
Flinn graduated from Huddersfield Technical College and worked at the Michelin-starred restaurant Lords of the Manor, in Gloucestershire, for two years.
He then moved to Barcelona to work alongside Xavier Pellicer at the Michelin-starred Abac restaurant before becoming the first, and only Englishman on the payroll at the El Bulli restaurant in Spain.
Taking to Twitter following the news this weekend, restaurant critic Jay Rayner said: "Sad news about the closure of Anthony Flinn's restaurants in Leeds. At a stroke it seriously reduces the eating options in that city."