Bocca di Lupo founders Jacob Kenedy and Victor Hugo have signed a deal on a new site on Cambridge Circus in London.
The two storey, 4,000 sq ft restaurant, to open in Spring 2015, will be "accessible and affordable" according to Kenedy.
Kenedy added: "I cannot wait to open, as I am confident the public will have as much fondness and love for our new concept as I do."
Charles Owen, Seven Dials portfolio manager at Shaftesbury, said: "Seven Dials' reputation, combined with the growing momentum behind Crossrail and the benefits that will bring, meant demand for this site from high quality operators was very strong. The concept from the founders of Bocca di Lupo stood out because of its originality and the way it complements the surrounding Seven Dials context."
The Seven Dials area of London has seen some notable openings of late, including Marcus Wareing's Tredwell's and Russell Norman's Ape and Bird.
JLL and Davis Coffer Lyons acted for Shaftesbury in the deal. Bocca Di Lupo represented themselves.