Gary McDermott, head chef of the Pentonbridge Inn, and four members of staff are understood to have walked out of the business just before service on Friday.
The restaurant with rooms in Carlisle, Cumbria was forced to close due to the departure of staff and has remained closed since.
A spokesperson for the Pentonbridge Inn said: "On the evening of Friday 30 November, we were forced to close the kitchen at Pentonbridge Inn with immediate effect following the unexpected departure of four members of our kitchen team. As we had no notice of this walkout, we were forced to rearrange hospitality where we possibly could for those guests who had reservations for that evening. This involved arranging transport to other local restaurants. Naturally, this has been incredibly disappointing for guests and we offer all those affected our unreserved apologies.
"The kitchen at Pentonbridge Inn is currently closed while we make alternative staffing arrangements and we are in touch with all guests affected by this situation."
The Pentonbridge Inn has been received well over the last year, including being shortlisted for The Caterer's Menu of the Year Award and being named Newcomer of the Year in the 2019 Good Hotel Guide.
The venue is owned by Gerald and Margo Smith, who also own nearby Netherby Hall.