Ten Hill Place in Edinburgh has completed its £8.5m expansion increasing its number of bedrooms from 77 to 129.
The hotel and neighbouring Hill Place buildings in the city's Old Town are owned by the Royal College of Surgeons of Edinburgh (RCSEd) and operated by the college's commercial arm, Surgeons Quarter, with profits going back into the college.
The hotel's executive chef Alan Dickson has also designed the hotel kitchen from scratch, complete with £150,000 of kitchen equipment.
Scott Mitchell, commercial director of Surgeons Quarter, said: "Our expansion will give us a greater platform to generate the profits that go directly towards improving lives for surgical patients all around the world - including those in areas of conflict and extreme poverty.
"As the number of visitors to Edinburgh has soared, we have been able to tap into the market and develop our reputation - meaning that the hotel is now busy all year round. Having initially targeted visiting academics, medical professionals and delegates to conferences; our customer base is now exceptionally varied."